Apatite Bio ceramic APA-90
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We have made apatite bio ceramic ball(diameter 10mm) by CIM, and confirmed performance of Pearl core material(Patent No.2958579) Please check SEM picture and properties below. Left side of picture is original apatite ball, Right side of picture is after put into a pearl shell. |
Sintered body
SEM picture(✕5000)
Nishimura No. | APA-90 | |
Main Component | Ca3(PO4)2 | |
Bulk Density | g/cm3 | 2.77 |
Bending Strenght | MPa | 30 |
(Reference:Bulk density of pearl is 2.65)
Application
Pearl core material(Patent No.2958579)
Based on our testing, we have checked a performance of this material to become a core of pearl.
This material is expected to be used as a alternative bone.
Nano Powder
Pulverized sintered apatite by a bead mill and freeze-drying.
For apply to cosmetic/ toothpaste/Quasi drag, We took a safety test by JFRL(Japan Food Research Laboratories)
Safety Test
For apply to cosmetic/ toothpaste/Quasi drag, We took a safety test by JFRL(Japan Food Research Laboratories)
Subject | Researching Laboratories | Test Content | Test Result | Notes |
Safety Test | JFRL |
Acute toxicity test (Rat,Both sexes) |
(LD50)>5000mg/kg | 5000mg/kg single dose, 14days Observation, OECD TG420(2001) conformity |
Primary skin irritation test (Rabbit) |
(Primary irritating index) 0<Nonstimulating> |
OECD TG404(2015) ISO10993-10:2010 conformity |
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Agents for treatment of oral mucosa(Guinea pig) |
(Visual observation) Not particular |
Suspension 800mg/mL 4times/day×Straight for four days |
CIM Apatite feedstock (Compound material for ceramic injection molding)
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Mixed Nishimura’s unique CIM binder with Apatite powder. Only thermal debinding is required, no liquid/chemical debinding. |